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San Francisco will be looking to keep up their fight for the NFL playoffs as they take on the Tennessee Titans this Sunday. San Francisco (9-4) has a slim lead over the Los Angeles Rams (11-8) and Seattle Seahawks (12-6) in the NFC West. Tennessee (2-11) could be the team to win the first pick of next year’s NFL Draft. Levi’s Stadium will kick off at 4:25 pm. ET. According to the latest Titans and 49ers odds the 49ers are 12.5 point favorites. The over/under total score is 44.5. Before making any Titans vs. 49ers picks of your own, make sure to look at the top NFL picks from the SportsLine Projection Model, which simulates every NFL game 10,000 times.
Where to watch Titans vs. 49ers on SundayWhen: Sunday, Dec. 14Time: 4:25 p.m. ETTV: FOXStream: FuboFollow along: CBS Sports AppTitans vs. 49ers betting previewOdds: 49ers -12.5, over/under 44.5While Tennessee is just 2-11 outright, it has managed to go 6-7 against the spread. The Titans have an 8-5 Over record. San Francisco has an 8-5 record ATS, and a 7-6 record to the Over. Both teams have covered four of their five last outings.
Model’s Titans and 49ers score predictions, picksSan Fransisco wins in 83% simulations. However, Tennessee has a better money line value of +600. The 49ers covered in 53%, and the Over hit in 67%, making this the model’s best pick.
You’ve already seen the model’s top picks for Tennessee Titans and San Francisco 49ers. Now, get against the spread, total and money-line picks for every Week 15 NFL game here, all from the model that’s simulated every game 10,000 times.
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2025-12-13 12:01:05
