This is the penultimate regular-season week for college football. Many top teams have opponents that they will easily be able to beat in the lead up to rivalry weekend. This weekend’s slate of games includes some tough matches, such as USC versus Oregon in the Big Ten Showdown. We’ll dive into the odds of college football Week 13 with DraftKings Sportsbook odds as of Nov. 21, and this page may include affiliate links to partners who offer legal sports betting. FOX Sports might be compensated for signing up or placing a wager. Learn more about Sports Betting at FOX Sports.(All times ET). 2 Missouri @ No. 8 Oklahoma (noon ABC)Point spread -6.5 Oklahoma (Oklahoma to cover if they win by more that 6.5 points)Moneyline Oklahoma -258 (obvious favorite to win) Missouri 210 (underdog to win)Total over/under: 42.5 combined points by both teams What to know: In Week 12, the Sooners upset Bama by a large margin in Tuscaloosa. They’re now the favorites to beat Mizzou in their own backyard. Tigers defense is one of best in college football but offense has been a regression since the beginning. Missouri has been 5-4-1 this year against the spread, but the team is likely to be without its starting quarterback Beau Pribula when they play in Norman. No. 7 Oregon (3:00, CBS)Pointspread: Oregon-10 (Oregon to win by at least 10 if USC does not cover)Moneyline (Oregon to win: -395; USC to win: +310)Total over/under: 59.5 combined points for both teamsWhat to know: The Ducks are 9-1 and look to be on their way to the College Football Playoff. Football Playoff. Upsetting the Ducks could help the 8-2 Trojans. SC defeated Iowa by 26-21 in Week 12. Oregon is coming off a 42-13 victory over Minnesota. The Ducks are at home, but their only loss this season came in Autzen when they lost to Indiana by 30-20. Michigan @ Maryland (4:30 p.m. BTN)Point Spread: Michigan -14. (Michigan is favored to cover by more than 14 if they win)Moneyline : Michigan +600 underdogs to win, Maryland -440 favorites to winTotal over/under: 46.5 total points scored by the two teams combined. Will the Wildcats cause UM to be a little nervous or keep the game closer than the double-digit line? Pittsburgh @ No. Georgia Tech (7:15 p.m. on ESPN)Point Spread: Georgia Tech +2.5 (Georgia Tech is favored by at least 2.5 points to win, otherwise Pittsburgh will cover)Moneyline : Georgia Tech as a -135 underdog; Pittsburgh as a 114 favorite to winTotal Score: 61.5 combined points by both teamsWhat to Know: The Yellow Jackets narrowly escaped Boston College with a victory of 36-34 last weekend. They will now face a Pitt squad that has dropped out of the Top 25 rankings after losing to Notre Dame by 37-15. The Jackets are currently the best offensive team in the country. This should give them a big advantage as they face BC’s worst defense. BYU at Cincinnati (8 pm, FOX). Point spread: BYU-2.5 (BYU to cover if they win by more than 2 points) Moneyline: BYU as a -135 underdog; Cincinnati as a 114 favorite. Total Over/Under for both teams: 55.5 total points. The Cougars only loss in a 9-1 season was to Texas Tech by 29-7. Their best victory was a 24-21 win over Utah. The Bearcats, the underdogs in this matchup, have three losses. Their best win was a 38-30 victory over Iowa State. To receive daily personalized news, create or log into your FOX account and follow teams, players, and leagues.
2025-11-21 14:44:42
College Football Week 13 Preview: Best Games to Watch this Weekend
