Michigan vs. Northwestern prediction, odds: Wrigley Field game picks from proven model

The Michigan Wolverines, ranked 21st in the Big Ten and College Football The Northwestern Wildcats will be the opponents in Saturday’s key conference game. Michigan won 21-16 over Purdue last Saturday, while Northwestern lost 38-17 to USC on Friday. The Wolverines, who are tied for the third spot in the Big Ten with USC and Oregon are 2-2 away this season. Wildcats (5-4 3-3 Big Ten), tied for ninth position in the league in 2025 and 4-1 in their own field, will be playing at Wrigley Field in Chicago. Michigan running back Justice Haynes is expected to be out. Kickoff is scheduled for noon ET at Wrigley Field, Chicago. The Wolverines hold a 10.5 point advantage over Northwestern in the most recent Michigan vs. Northwestern betting odds. While the total score is at 41.5 points, the Wolverines’ favorite by 10.5 points. Before making any Northwestern vs. Michigan picks, check out the college football predictions from the SportsLine Projection Model. New users can target the DraftKings promo code, which offers $300 in bonus bets if your bet wins + 3 months of NBA League Pass:The model simulates every FBS game 10,000 times. Since its creation, the model has generated betting profits of over $2,000 per $100 bet on its best college football picks. Anybody following its college football betting picks at sportsbooks and on betting sites could have seen strong returns.Now, the model has set its sights on Michigan vs. Northwestern. To see the picks, visit SportsLine. Here are the FBS college football odds and trends for Northwestern vs. Michigan:Michigan vs. Northwestern spreadMichigan -10.5 at DraftKings SportsbookMichigan vs. Northwestern over/under41.5 pointsMichigan vs. Northwestern money line Michigan -431, Northwestern +331Michigan vs. Northwestern picksSee picks at SportsLineMichigan vs. Northwestern streaming Fubo (Try for free)  New users can also check out the latest FanDuel promo code and get $150 in bonus bets at FanDuel if your $5 bet wins. How to pick Michigan vs. Northwestern SportsLine’s model predicts that the total will go over (41.5 points). Northwestern has been over in both of its last two games. The over has also hit in four out of eight previous meetings between these teams. Michigan quarterback Bryce Underwood should throw for at least one touchdown, and Wolverines runningback Jordan Marshall should surpass 125 rushing yards during the model’s simulations. Northwestern quarterback Preston Stone will also throw for a touchdown, as well as more than 150 passing yards. Over is the better side as the teams combined for 43 points. Only SportsLine offers the pick. Who will win Michigan vs. Northwestern and which side hits the spread well over 50% of time? Discover which side of the Michigan-Northwestern spread you should bet, based on the model that has won over $2,000 in college football betting since its creation.

2025-11-15 12:21:16