NFL Week 10 features two sets of division leaders in a showdown. On Sunday the AFC East leading New England Patriots led by quarterback Drake Maye face the NFC South leading Tampa Bay Buccaneers, and quarterback Baker Mayfield. Monday Night FootballJalen’ Hurts, the Philadelphia Eagles quarterback, will be leading the Philadelphia Eagles onto Lambeau Field in order to take on Jordan Love and his Green Bay Packers. Tampa Bay is a 2.5-point favorite, as are the Green Bay Packers. Los Angeles Rams (6-2) travel to San Francisco in order to play the 49ers (6-3). This is a crucial NFC West matchup. Matthew Stafford is 4.5 points favorite to make up for a 26-23 overtime defeat to San Francisco. He’s won three out of his four previous starts against the 49ers. Jets vs. Browns has seen the most line movement, as Cleveland moved from a 2.5-point underdog to a 2.5-point favorite after New York unloaded Sauce Gardner and Quinnen Williams in separate trades on Tuesday. The game with the most line movement has been Jets vs. Browns, with Cleveland moving from a 2.5-point underdog to 2.5-point favorite after New York unloaded Sauce Gardner and Quinnen Williams in separate trades on Tuesday.Before making any Week 10 NFL picks or NFL score predictions on those games or others, you need to see the NFL against the spread, over/under and money line predictions powered by the self-learning SportsLine AI.New users can target the DraftKings promo code, which offers $300 in bonus bets if your bet wins + 3 months of NBA League Pass:Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine’s Data Science team, AI Predictions and AI Ratings are generated for each game. AI ratings and predictions are calculated by the SportsLine Data Science team by using machine learning and artificial intelligence techniques to analyze historical data. It constantly updates the latest data available and can help you identify the largest discrepancies between the lines. SportsLine’s AI PickBot made more than 2,000 props with 4.5 and 5 stars since the 2023 season. For Week 10 NFL betting, the AI PickBot has evaluated the NFL odds and provided NFL betting picks for all 14 games. You can only see the AI predictions for the Week 10 NFL schedule here.New users can also target the latest Underdog promo code, good for $100 in bonus entries when you play $5 with the promo code CBSSPORTS2 in select states.Top Week 10 NFL AI picksAfter analyzing every game in Week 10, the AI says the Buffalo Bills (-9.5) cover comfortably against the Miami Dolphins, who may be on their way to a rebuild. Josh Allen, the Buffalo offensive leader, has a 70.4% completion rate on his passes. This has led to 1,833 yards of total offense and 13 touchdowns. There have been four interceptions. He has also run 55 times (5.2 average) for 280 yards and seven touchdowns. Two of those came in the 28-21 victory over Kansas City Chiefs.Miami is struggling of late. They have lost four of their five last games, including the 28-6 loss they suffered to Baltimore Ravens Thursday night. Football On Oct. 30, the Dolphins parted ways with longtime general manager Chris Grier. After the game, Dolphins general manager Chris Grier was fired. SportsLine AI, despite James Cook’s (ankle injury) absence from practice on Wednesday still rates the Bills at an A+ and predicts that they will win 36-22 on average. SportsLine has other football predictions for Week 10 and picks. Bet on the Bills by clicking here. Before you place any Week 10 NFL wagers, it is important to check out the AI’s NFL predictions. Only SportsLine has them. Who wins and covers every Week 10 NFL game? And which A+ selections should you be targeting now? Visit SportsLine to view the top NFL picks for the week 10 games against the spread, the over-under and the money line. All from the SportsLine AI, which has made more than 2,000 high-rated predictions since the start the season in 2023.
2025-11-06 02:59:22
